Zyban and Interactions with Other Medications

Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal remedies, and supplements, before starting Zyban (bupropion).

Certain medications can significantly affect how Zyban works or increase the risk of side effects. Here are some key examples:

    MAO Inhibitors: Never take Zyban if you’re currently using, or have recently stopped using, a monoamine oxidase inhibitor (MAOI). A dangerous interaction can occur, potentially leading to serious health consequences. Seizure Medications: Zyban may lower the seizure threshold. If you have a history of seizures or are taking medications to prevent seizures, discuss the risks with your doctor before starting Zyban. Other Antidepressants: Combining Zyban with other antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), can increase the risk of serotonin syndrome, a potentially life-threatening condition. Careful monitoring is needed. Warfarin: Zyban may interact with warfarin, a blood thinner. Your doctor might need to adjust your warfarin dose if you start taking Zyban. Alcohol: Alcohol can intensify Zyban’s side effects. Limit your alcohol consumption while using Zyban.

This isn’t an exhaustive list. Many other medications can interact with Zyban. Open communication with your healthcare provider is crucial for safe and effective use.

Provide your doctor with a complete medication list. Report any new or worsening symptoms promptly. Follow your doctor’s instructions precisely.

Your doctor can help you assess potential interactions and adjust your medication regimen accordingly. Your safety is paramount.