Side Effects Comparison: Zytiga with and without Prednisone

Predicting individual side effect profiles is impossible, but general trends exist. While Prednisone adds its own side effects, it can also modify how patients experience Zytiga’s effects. Here’s a comparison:

Side Effect Zytiga Alone Zytiga with Prednisone
Fatigue Common; can be severe. Potentially increased; Prednisone itself causes fatigue.
Diarrhea Frequent; often manageable with medication. May be slightly lessened or unchanged. Prednisone can sometimes cause diarrhea, complicating management.
High Blood Sugar (Hyperglycemia) Possible; monitor blood sugar regularly. Significantly increased risk; careful monitoring and management required.
High Blood Pressure (Hypertension) Possible; monitor blood pressure regularly. Increased risk; Prednisone contributes to hypertension.
Muscle Aches/Weakness Common; range from mild to debilitating. Can be worsened by Prednisone’s muscle-weakening effects.
Weight Gain Common; fluid retention plays a role. Increased risk due to fluid retention from both drugs.
Increased Risk of Infection Increased; immune system suppression. Increased further; Prednisone suppresses the immune system.
Heart problems Possible; monitor cardiac health. Increased risk, particularly fluid retention-related problems.

Consult your doctor to discuss potential benefits and risks of either treatment regimen tailored to your specific health condition and risk factors. Careful monitoring of blood sugar, blood pressure, and overall health is crucial regardless of the chosen treatment approach. This information should not replace medical advice; always prioritize discussions with your healthcare team.