Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the propionic acid derivative class. It effectively reduces pain, fever, and inflammation.
Uses of Ketoprofen
Doctors prescribe ketoprofen to manage various conditions. These include: acute pain (such as post-surgical pain or musculoskeletal pain), osteoarthritis, rheumatoid arthritis, and dysmenorrhea (painful menstruation). It’s also sometimes used to treat fever.
Mechanisms of Action
Ketoprofen’s pain-relieving and anti-inflammatory effects stem from its ability to inhibit cyclooxygenase (COX) enzymes. COX enzymes produce prostaglandins, molecules that mediate inflammation and pain. By blocking COX, ketoprofen reduces prostaglandin production, thus alleviating these symptoms.
| COX-1 | Reduced protection of the stomach lining, potentially leading to gastrointestinal side effects. |
| COX-2 | Reduced inflammation and pain. |
It’s important to note that ketoprofen, like other NSAIDs, carries potential risks such as gastrointestinal upset, kidney issues, and cardiovascular problems. Always consult a doctor before using ketoprofen, especially if you have pre-existing health conditions.
Dosage and Administration
Ketoprofen is available in various forms including tablets, capsules, and topical gels. Dosage depends on the specific condition and the patient’s health. Your doctor will determine the appropriate dosage and administration method.
