Viagra’s Mechanism of Action and its Impact on Erection

Viagra, or sildenafil, works by inhibiting a specific enzyme called phosphodiesterase-5 (PDE5). This enzyme normally breaks down cyclic guanosine monophosphate (cGMP), a crucial molecule for achieving and maintaining an erection.

By blocking PDE5, Viagra allows cGMP levels to rise. Increased cGMP relaxes the smooth muscles in the blood vessels of the penis, increasing blood flow. This increased blood flow engorges the penis, leading to an erection.

The duration and intensity of the erection depend on several factors, including the individual’s overall health, the dose of Viagra taken, and other medications being used. It’s crucial to follow your doctor’s instructions carefully.

Factor Impact on Erection
Increased cGMP Relaxed penile smooth muscles
Increased Blood Flow Penile engorgement
PDE5 Inhibition Prolonged cGMP effects

It’s important to note that Viagra does not directly cause an erection; it facilitates the natural erectile response by enhancing blood flow to the penis. Sexual stimulation is still required to initiate the process.