Zofran Interactions: Medications and Substances to Avoid

Always inform your doctor or pharmacist about all medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, before starting Zofran. This prevents potential harmful interactions.

Specifically, Zofran can interact negatively with certain medications that affect the heart’s rhythm, such as amiodarone or quinidine. Concurrent use may increase the risk of heart problems.

Avoid consuming alcohol while on Zofran. Alcohol can exacerbate Zofran’s side effects, potentially causing increased drowsiness or dizziness.

Theophylline, a medication used to treat asthma and COPD, can have its effects altered when taken with Zofran. Monitor for changes in your breathing or other symptoms.

Combining Zofran with certain antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), might increase the risk of serotonin syndrome, a potentially life-threatening condition. Discuss this risk with your healthcare provider.

Grapefruit juice can interact with many medications, and Zofran is no exception. Avoid grapefruit juice while taking Zofran to prevent unexpected changes in the medication’s effectiveness.

This information is not exhaustive. Consult your doctor or pharmacist for a complete list of potential interactions and personalized advice.