Hyperphosphatemia, or high phosphate levels in the blood, is a serious concern for people with chronic kidney disease (CKD). Untreated, it contributes to cardiovascular disease, bone disease, and increased mortality.
Renagel (sevelamer) and Renvela (sevelamer carbonate) are phosphate binders. They work by preventing the absorption of phosphate from your food in your intestines. This helps lower your blood phosphate levels. Your doctor will determine the right medication and dosage based on your individual needs and lab results.
Choosing Between Renagel and Renvela
Both medications contain sevelamer, but Renvela is better tolerated by some patients due to its carbonate form reducing the risk of gastrointestinal side effects, such as constipation and nausea. However, Renvela often costs more than Renagel. Discuss the cost and potential benefits with your doctor to find the best option for your situation.
Monitoring Phosphate Levels
Regular blood tests are crucial to monitor your phosphate levels. This allows your doctor to adjust your medication dosage, ensuring your phosphate levels remain within a healthy range. Maintaining appropriate phosphate control helps prevent complications of CKD.
| Renagel | Sevelamer hydrochloride | Constipation, nausea, vomiting |
| Renvela | Sevelamer carbonate | Constipation, nausea, vomiting (generally less frequent than with Renagel) |
Always follow your doctor’s instructions regarding medication use and follow-up appointments.
