Combining Sudafed (pseudoephedrine) and prednisone requires caution. Pseudoephedrine is a decongestant that raises blood pressure. Prednisone, a corticosteroid, can also elevate blood pressure and increase blood sugar.
This combination may exacerbate hypertension, especially in individuals with pre-existing high blood pressure or diabetes. Closely monitor your blood pressure while taking both medications.
Increased blood sugar is another potential concern. Prednisone’s effect on blood glucose levels can be amplified by the stress response, potentially worsening conditions like diabetes. Regularly check your blood sugar if you have diabetes or risk factors.
Both medications can cause insomnia. Consider taking Sudafed earlier in the day to minimize sleep disruption. Prednisone’s effects on sleep vary by individual.
Consult your doctor before using these drugs together, especially if you have heart conditions, diabetes, or high blood pressure. They can help you manage the potential risks and adjust dosage as needed.
Your pharmacist can also provide helpful information and address your specific concerns about potential drug interactions.
