The antagonist protocol using Clomid typically begins on cycle day 2 or 3 with GnRH antagonist injections. These injections, usually Cetrotide or Ganirelix, start around the time your follicles reach a certain size (usually 14mm). The exact day will depend on your individual response to stimulation, closely monitored via ultrasound and blood tests. Dosage for GnRH antagonists varies depending on the specific medication and your doctor’s assessment, but it’s typically a daily injection.
Clomid Administration
Clomid, an oral medication, is usually started on cycle day 3-5 and continued for 5 days, though your doctor may adjust this based on your response. The typical dosage is 50mg daily, but this can be increased to 100mg daily if follicle growth is insufficient. Remember, the goal is to stimulate multiple follicles of appropriate size for egg retrieval. Over-stimulation is a risk, hence the importance of careful monitoring.
Trigger Shot
Once your follicles reach optimal size (usually 18mm), a trigger shot of hCG (human chorionic gonadotropin) is administered. This injection triggers final egg maturation and ovulation. The timing of this injection is critical and determined by your doctor based on your follicle development and other factors, such as estrogen levels. Following the trigger shot, egg retrieval occurs 34-36 hours later. Always carefully follow your doctor’s instructions regarding medication timing. Individualized protocols are common.
Monitoring and Adjustments
Regular monitoring via ultrasound and blood tests is crucial throughout the antagonist protocol. This allows your doctor to assess follicular growth, hormone levels, and adjust medication dosage as needed to optimize the chance of successful egg retrieval. Do not hesitate to contact your clinic with any concerns or questions.
