Sildenafil can interact with several medications. Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal remedies, and supplements. This helps avoid potential complications.
Certain medications significantly increase the risk of side effects when combined with sildenafil. These include nitrates (used to treat chest pain), alpha-blockers (used to treat high blood pressure and enlarged prostate), and some antifungals. Combining these can cause a dangerous drop in blood pressure.
Other medications may affect sildenafil’s effectiveness or increase the likelihood of side effects. These include:
| CYP3A4 inhibitors | Ketoconazole, erythromycin, ritonavir | Increased sildenafil levels, potentially enhancing side effects. |
| CYP3A4 inducers | Rifampin, St. John’s Wort | Decreased sildenafil levels, potentially reducing effectiveness. |
| Protease inhibitors | Indinavir, ritonavir | Increased sildenafil levels, requiring potential dose adjustment. |
This information is not exhaustive. Consult your doctor or pharmacist for a personalized assessment of potential interactions based on your specific medical history and current medications.
