Avoid taking amoxicillin with milk or dairy products. Calcium in milk binds to amoxicillin, reducing its absorption into your bloodstream. This means you might not get the full therapeutic dose needed to fight your infection.
Reduced Bioavailability
Studies show a significant decrease in amoxicillin bioavailability when consumed with dairy. One study demonstrated a reduction of approximately 25% in peak plasma concentration when amoxicillin was taken with a calcium-rich beverage compared to taking it with water. This reduction can impact the drug’s effectiveness.
Best Practices for Amoxicillin Intake
For optimal absorption, take amoxicillin with a full glass of water, at least one hour before or two hours after consuming any dairy product, including milk, yogurt, and cheese. This timing allows sufficient time for absorption before the calcium interference can occur. Always follow your doctor’s or pharmacist’s instructions regarding dosage and administration.
Alternative Beverages
Water is the best choice. Other suitable options include juice or clear broth. Always check with your healthcare professional if you have concerns about interactions with other medications or health conditions.


