Schedule an appointment immediately if you experience any severe side effects. This includes but isn’t limited to: severe acne flares, intense itching, significant vision changes, persistent nausea, or unusual bleeding.
Consult your dermatologist before starting either Accutane or doxycycline if you have a history of:
| Liver disease | Accutane can affect liver function. |
| Kidney disease | Both medications can be processed by the kidneys. |
| Pregnancy or breastfeeding | Accutane is teratogenic and doxycycline can pass into breast milk. |
| Depression or anxiety | Accutane has been linked to mood changes. |
| Sun sensitivity | Doxycycline can increase sun sensitivity. |
| Other medication use | Potential drug interactions exist. |
Regular check-ups with your dermatologist are necessary while on this combination therapy. This allows for monitoring of your skin condition, liver function, and overall health. Blood tests might be required to assess these factors. Report any changes in your health promptly to your doctor.
If you have questions or concerns about the combination of Accutane and doxycycline, or experience any unexpected symptoms, contact your dermatologist without delay.


