Accutane, the brand name for isotretinoin, works by significantly reducing sebum production. Sebum is an oily substance produced by your skin’s oil glands; excess sebum contributes significantly to acne development. Isotretinoin achieves this reduction by impacting sebaceous gland size and activity.
How Isotretinoin Affects Acne
Beyond sebum reduction, isotretinoin also combats acne by decreasing inflammation and preventing the formation of comedones (blocked pores). It alters the properties of skin cells, preventing them from sticking together and forming blockages. This dual action tackles both the underlying causes and visible symptoms of acne.
Important Considerations
Isotretinoin is a potent medication, and its use requires close monitoring by a dermatologist. Potential side effects include dry skin, lips, and eyes; increased sun sensitivity; and temporary hair thinning. Furthermore, pregnant or breastfeeding women should absolutely avoid isotretinoin due to severe birth defects risks. Always discuss potential risks and benefits with your doctor before starting treatment.


