Prednisone weakens your immune system, increasing your susceptibility to infections. Common infections include pneumonia, bronchitis, and urinary tract infections. Serious infections like tuberculosis or fungal infections are also possible, especially in individuals with pre-existing conditions. Monitor yourself for fever, cough, or unusual fatigue; seek immediate medical attention if you suspect an infection.
Opportunistic Infections
Prednisone’s immunosuppressive effects allow opportunistic infections to thrive. These are infections caused by microorganisms that normally don’t cause illness in people with healthy immune systems. Examples include shingles (herpes zoster), candidiasis (thrush), and cytomegalovirus (CMV). Prevention involves regular hygiene practices and careful monitoring for symptoms. Your doctor might recommend preventative measures, like antiviral medications, depending on your individual risk factors.
Other Immunosuppression-Related Risks
Beyond increased infection risk, prednisone can lead to delayed wound healing. This is because the drug hinders the body’s natural repair processes. Avoid unnecessary skin trauma and keep wounds meticulously clean. Additionally, prednisone can aggravate existing autoimmune diseases. It might temporarily improve symptoms, but long-term usage can worsen the underlying condition. Open communication with your physician is paramount for careful monitoring and management.


