Never combine nitroglycerin and Cialis. This combination significantly increases your risk of dangerously low blood pressure (hypotension).
Both medications lower blood pressure. Cialis, a phosphodiesterase-5 (PDE5) inhibitor, relaxes blood vessels. Nitroglycerin, a nitrate, does the same, often much more powerfully. The combined effect can cause a sudden and dramatic drop in blood pressure, leading to dizziness, fainting, and even a heart attack or stroke.
Symptoms of severe hypotension include lightheadedness, nausea, weakness, and blurred vision. If you experience any of these after taking both medications, seek immediate medical attention. Do not drive or operate machinery.
Consult your doctor before starting any new medication, particularly if you already take nitroglycerin or other heart medications. They can assess your individual risk and help you create a safe medication plan.
If you accidentally take both medications, contact your doctor or a poison control center immediately. Timely intervention is crucial in managing this potentially life-threatening interaction.
Remember: Always inform all healthcare providers about all medications you are taking, including over-the-counter drugs and supplements. This helps prevent dangerous drug interactions.


