Measure blood pressure frequently, initially at least daily, then adjust the frequency based on patient response and stability. Target blood pressure should be determined individually, considering patient-specific factors and comorbidities.
Initial Monitoring: Begin with frequent monitoring, ideally within 1-2 hours of the first dose and then again after 6 hours. This establishes a baseline and helps detect early adverse effects.
Post-Dose Monitoring: After initial monitoring, check blood pressure at least once daily for the first week of treatment. Pay close attention to orthostatic hypotension – check both supine and standing blood pressure.
Frequency Adjustments: Reduce monitoring frequency to every other day after the first week if the patient is stable and tolerates treatment well. However, more frequent checks may be needed for patients at higher risk for hypotension or those showing signs of treatment intolerance.
Home Monitoring: Encourage patients to monitor blood pressure at home with a validated home blood pressure monitor, especially if they experience dizziness or lightheadedness. Patients should keep a record of these measurements and share them with their healthcare provider.
Clinical Signs: Watch for signs of hypotension such as dizziness, lightheadedness, fainting, or weakness. These necessitate immediate blood pressure checks and may require dose adjustment or discontinuation of Diltiazem.
Dosage Adjustments: Blood pressure readings guide dosage adjustments. If blood pressure is too low, the dose may need reducing. If it’s not adequately controlled, the dose may need increasing. Always follow prescribing guidelines and make changes in consultation with a healthcare professional.
Remember: Regular monitoring empowers both patient and healthcare provider to optimize therapy and minimize adverse events associated with Diltiazem.


