Lisinopril’s Primary Uses and Mechanism of Action

Lisinopril primarily treats hypertension (high blood pressure) and heart failure. It’s also used after a heart attack to reduce the risk of death.

How Lisinopril Works

Lisinopril is an ACE inhibitor. It works by blocking the production of angiotensin II, a hormone that narrows blood vessels. By inhibiting angiotensin II, lisinopril allows blood vessels to relax and widen, lowering blood pressure and reducing the workload on the heart. This improved blood flow benefits both heart failure patients and those recovering from a heart attack. Lower blood pressure directly reduces strain on the heart, improving its function.

Specific Indications

Beyond hypertension and heart failure, lisinopril helps prevent kidney disease in patients with diabetes and helps prevent strokes in some high-risk individuals. Your doctor will determine if lisinopril is the right medication for your specific needs based on your health history and condition.